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L-Glutathione is a naturally occurring tripeptide (γ-L-glutamyl-L-cysteinylglycine) that plays a central role in intracellular antioxidant defense and redox regulation. It is involved in cellular detoxification processes, protection against oxidative damage, and maintenance of metabolic balance through regulation of reactive oxygen species and thiol homeostasis. L-Glutathione is widely utilized in biochemical and cellular research investigating oxidative stress responses, redox signaling mechanisms, and glutathione-dependent enzymatic pathways.
For research use only. Not for human consumption.
References:
Forman HJ et al., Free Radical Biology & Medicine, 2009; 47(10):1304–1313
Lu SC, Molecular Aspects of Medicine, 2009; 30(1–2):42–59
Pompella A et al., Biochemical Pharmacology, 2003; 66(8):1499–1503
L-Glutathione is a naturally occurring tripeptide composed of glutamic acid, cysteine, and glycine. It plays a central role in intracellular redox regulation and cellular defense mechanisms. In laboratory research, L-Glutathione is widely studied for its involvement in oxidative balance, detoxification pathways, and maintenance of cellular homeostasis.
Biochemical Characteristics
L-Glutathione contains a reactive thiol group that enables it to participate in redox reactions and antioxidant processes. This structural feature allows it to neutralize reactive oxygen species and maintain thiol equilibrium within cells. Its tripeptide structure supports interaction with various enzymes involved in redox cycling and cellular protection mechanisms.
Research Applications
L-Glutathione is commonly used in biochemical and cellular research focused on oxidative stress response, antioxidant systems, and detoxification pathways. It is applied in studies examining cellular defense mechanisms, glutathione-dependent enzymatic reactions, and redox signaling processes under controlled laboratory conditions.
Pathway / Mechanistic Context
Mechanistic research involving L-Glutathione explores its role in redox homeostasis, regulation of oxidative stress, and modulation of cellular signaling pathways. Studies focus on its participation in maintaining intracellular redox balance and supporting enzymatic systems involved in detoxification and metabolic regulation.
Preclinical Research Summary
Preclinical investigations have evaluated L-Glutathione in various in vitro and experimental models to better understand its biochemical behavior and role in cellular protection. These studies support its continued use as a research tool for exploring antioxidant defense systems and redox-related cellular responses.
Form & Analytical Testing
L-Glutathione is supplied in a purified form and undergoes analytical testing, including HPLC, to verify identity, purity, and consistency. Analytical validation ensures suitability for laboratory research requiring accurate biochemical characterization.
RUO Disclaimer
This product is intended for research and laboratory use only. It is not approved for human consumption, medical treatment, veterinary use, cosmetic application, or diagnostic purposes. Handling should be performed only by qualified professionals trained in proper laboratory procedures.
| Strength | 600 mg, 1500 mg |
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