Price range: $60.00 through $180.00
HGH-191AA (Somatotropin) is a recombinant 191–amino acid polypeptide identical in sequence to endogenous human growth hormone and studied for its interaction with the growth hormone receptor (GHR) in experimental endocrine models. It is investigated for its role in activating JAK-STAT signaling and insulin-like growth factor-1 (IGF-1)–associated pathways. Preclinical research utilizes HGH-191AA to examine receptor binding kinetics, downstream transcriptional regulation, and somatotropic axis modulation under controlled laboratory conditions.
For research use only. Not for human consumption.
References:
Waters MJ et al., Endocr Rev, 1999
Le Roith D et al., Endocr Rev, 2001
Brooks AJ et al., Nat Rev Endocrinol, 2016
HGH-191AA is a full-length recombinant human growth hormone studied in laboratory research focused on growth factor signaling and endocrine regulatory pathways. It serves as a research tool for examining somatotropic axis activity and receptor-mediated signaling mechanisms.
Biochemical Characteristics
HGH-191AA is a single-chain 191–amino acid polypeptide that binds to the growth hormone receptor (GHR). Upon receptor engagement, it promotes receptor dimerization and activation of intracellular signaling cascades in experimental systems.
Research Applications
HGH-191AA is utilized in research models investigating GHR activation, IGF-1 pathway signaling, metabolic regulation mechanisms, and transcriptional responses associated with growth hormone–mediated signaling.
Pathway / Mechanistic Context
Mechanistic research focuses on GHR-mediated activation of JAK-STAT signaling pathways and downstream gene expression events influencing growth factor coordination and metabolic regulation.
Preclinical Research Summary
Preclinical investigations have evaluated HGH-191AA in in vitro and experimental models to better understand receptor-mediated endocrine signaling and growth hormone pathway dynamics.
Form & Analytical Testing
HGH-191AA is supplied as a lyophilized recombinant peptide and undergoes analytical verification, including purity and identity testing, to confirm structural integrity suitable for laboratory research use.
RUO Disclaimer
This product is intended strictly for research and laboratory use only. It is not approved for human consumption, medical treatment, veterinary use, cosmetic application, or diagnostic purposes. Handling should be performed only by qualified professionals trained in proper laboratory procedures.
| Strength | 10iu, 15iu, 24iu, 36iu |
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